East Fife welcome back one-time Scotland defender Robbie Neilson as they host Rangers for the very first time at their 15-year-old New Bayview Stadium.
Neilson sat out last weekend's 2-1 success at Dunfermline, however he has been passed fit to play in front of a record 4,700 attendance in Methil.
Not such good news is that Paul Willis is out with a foot injury and former Rangers midfielder Stephen Hughes is struggling to make it due to a knock.
Manager Willie Aitchison said: "We had a game plan that worked very well at Dunfermline and now have to come up with a game plan to stop Rangers."
Rangers are likely to be boosted by the return of Lee Wallace and Arnold Peralta for the game.
Wallace has been struggling with a knee injury while Peralta was unwell following his return from international duty with Honduras, but both should be back in contention.
Chris Hegarty and Ross Perry (both ankle) remain on the sidelines, with Perry set to go under the knife to cure the problem.