Everton, the last British club left in this season's Europa League, have been drawn against Ukrainian side Dynamo Kiev in the competition's round of 16.
Roberto Martinez's side, who demolished Young Boys 7-2 on aggregate in the round of 32, will play the first leg of the tie at Goodison Park.
Inter Milan travel to new tournament favourites Wolfsburg in the first leg of their quarterfinal, while the draw also threw up all-Italian and all-Spanish ties.
Fiorentina, who knocked Tottenham out of the competition with a 3-1 aggregate scoreline, play Roma at home in the first leg, while Villarreal host Sevilla.
Liverpool's conquerors Besiktas have been drawn away to Belgian outfit Brugge.
Round of 16: Ties to be played March. 12 and 19: