Manchester United striker Danny Welbeck has been ruled out of England's friendly with Sweden on Tuesday due to a muscle strain.
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Welbeck was expected to be included from the start at Wembley, but has now returned to his club in order to undergo treatment on the injury.
His withdrawal opens the door for Chelsea striker Daniel Sturridge, who Capello has confirmed will play at some point, to make his international debut. He is likely to partner Fulham forward Bobby Zamora upfront as England look to build on their 1-0 victory over Spain at the weekend.
Welbeck has been earmarked as a potential replacement for Wayne Rooney at the tournament in Poland and Ukraine, with Rooney suspended for the first three matches following a red card against Montenegro during qualifying.
Welbeck, 20, has started seven times in the Premier League for United this season, scoring three goals and contributing two assists. His form has meant Dimitar Berbatov, a £30 million signing from Tottenham, has made just one league start.
Following an impressive loan spell at Bolton last season, Sturridge has forced his way into the first-team picture at Stamford Bridge, netting four in seven league starts, and is set to be rewarded for his performances.