Manchester City midfielder Patrick Vieira, Manchester United's Owen Hargreaves, West Ham defender Matthew Upson and Tottenham's Jonathan Woodgate are some of the bigger names to be released by their clubs this summer.
The Premier League has published its lists of retained players and those available on a free transfer this summer and it is no surprise to see the three relegated clubs - Birmingham, West Ham and Blackpool - offloading 32 players between them.
Age has finally caught up with Vieira, who is 35 next week, and he is joined on the exit list at Eastlands by Javier Garrido and former academy graduate Shaleum Logan.
Hargreaves' departure from United was fully expected as injury restricted him to just 11 minutes' football in the last two seasons
Woodgate suffered similar problems, making just four appearances in two years.
Birmingham have let a dozen players go, with the likes of Lee Bowyer, Sebastian Larsson, James McFadden, Kevin Phillips and Maik Taylor on their list of free transfers.
West Ham's England international Upson, Wales centre-back Danny Gabbidon, defender Lars Jacobsen and Jonathan Spector have all been put on the open market, while Blackpool midfielder David Vaughan's rejection of a new contract means he joins 11 others leaving Bloomfield Road.
Bolton had already announced Johan Elmander, Ricardo Gardner and Jlloyd Samuel would be leaving.
Stoke have released Eidur Gudjohnsen and Ibrahima Sonko, with veteran Dutchman Bolo Zenden leaving Sunderland and Abdoulaye Meite West Brom.
Wolves midfielder Dave Jones, veteran defender Jody Craddock and goalkeeper Marcus Hahnemann are all departing Molineux, while Wigan have released Steven Caldwell, Daniel de Ridder, Jason Koumas and veteran goalkeeper Mike Pollitt.
FULL RELEASED LIST
Thomas Cruise, Roarie Deacon, Mark Randall
Durrell Berry, John Carew, Ellis Deeney, Calum Flanagan, Harry Forrester, Arsenio Halfhuid, Isaiah Osbourne, Robert Pires, Nigel Reo-Coker, Moustapha Salifou
Marcus Bent, Lee Bowyer, Sebastian Larsson, James McFadden, Mitchell McPike, James O'Shea, Stuart Parnaby, Kevin Phillips, Daniel Preston, Luke Rowe, Robin Shroot, Maik Taylor
Jordan Bowen, Jason Brown, Zurab Khizanishvili, Benjani Mwaruwari, Michael Potts, Maceo Rigters
David Carney, Daniel Coid, Ishmel Demontagnac, Rob Edwards, Jason Euell, Marlon Harewood, Richard Kingson, Malaury Martin, Paul Rachubka, Andy Reid, Salaheddine Sbai
Tamir Cohen, Johan Elmander, Ricardo Gardner, Joey O'Brien, Jlloyd Samuel, Samuel Sheridan
Samuel Hutchinson, Carl Magnay, Danny Philliskirk, Jan Sebek, Michael Woods
Kieran Agard, Hope Akpan, Nathan Craig, Gerard Kinsella, Lee McArdle, Iain Turner
Zoltan Gera, Eddie Johnson, Diomansy Kamara, John Pantsil, Matthew Saunders
Jason Banton, Deale Chamberlain, Douglas Cooper, Sean Highdale, Steven Irwin, Nikola Saric
Javier Garrido, Scott Kay, James Poole, Shaleum Logan, Andrew Tutte, Javan Vidal, Patrick Vieira, James Wood
Conor Devlin, Owen Hargreaves, Gary Neville, Paul Scholes, Edwin van der Sar
Sol Campbell, Shefki Kuqi, Patrick McLaughlin
Abdoulaye Faye, Eidur Gudjohnsen, Ibrahima Sonko
Michael Kay, Nathan Luscombe, Daniel Madden, Robert Weir, Nathan Wilson, Mvoto Jean-Yves, Bolo Zenden
West Bromwich Albion
Giles Barnes, Marcus Haber, Dean Kiely, Abdoulaye Meite
West Ham United Anthony Edgar, Holmar Eyjolfsson, Daniel Gabbidon, Lars Jacobsen, Filip Modelski, Jonathan Spector, Adam Street, Matthew Upson
Steven Caldwell, Daniel De Ridder, Joseph Holt, Jason Koumas, Thomas Lambert, Thomas Oakes, Francis Pollitt, Abian Serrano Davila
Adriano Basso, Jody Craddock, John Dunleavy, Marcus Hahnemann, David Jones, Nathan Rooney