Olympique Lyon further undermined their chances of recapturing the Ligue 1 title after a 1-1 draw at Monaco dropped them 10 points behind leaders Girondins Bordeaux on Sunday.
Seven-times champions Lyon, who lost their crown to Bordeaux last May, started well, Brazilian midfielder Michel Bastos putting them ahead with a super angled free kick on 22 minutes.
The home side, however, earned a share of the points when Korean forward Park Chu-young volleyed home a Sebastien Puygrenier headed pass 12 minutes later.
Monaco were clearly the better team in the second half, Lyon looking only a pale shadow of the side who ruled France for seven seasons.
Three goals in the first half an hour against Le Mans gave Lille their fifth win a row and lifted them up to third in the Ligue 1 table.
They might have had more had Florent Balmont not missed a 14th minute penalty, moments after Aurelien Chedjou had put them in front with a header. Gervinho added a second in the 27th minute before Eden Hazard completed the scoring with only 29 minutes gone.
Roy Contout's late leveller earned Auxerre a point against Toulouse - their third Ligue 1 draw in a row.
Luan had given Toulouse the lead, somewhat against the run of play, with his first Ligue 1 goal as they sought to recover from their midweek Europa League exit. Les Violets looked like holding on until Etienne Didot was dismissed for a second yellow five minutes from time.