Dutch midfielder Wesley Sneijder strained ankle ligaments in Saturday's 3-0 friendly win over Japan and is doubtful for Wednesday's World Cup qualifier against Scotland.
Inter Milan's Sneijder was taken to hospital for checks immediately after the game and a spokeswoman for the Dutch team said a decision had not yet been taken on whether he would rejoin the squad. Dutch coach Bert van Marwijk had earlier expressed concern about the injury.
"Wesley told me he heard something crack so it looks serious but we have to await the outcome of the investigation in the hospital," he told reporters.
Sneijder scored his side's second goal, between strikes from Robin van Persie and Klaas Jan Huntelaar, in a low-key win. The Dutch have already qualified for the 2010 World Cup in South Africa and the Scotland match is their last one in Group Nine.