Newcastle United have been relegated from the Premier League after a 1-0 defeat at Aston Villa.
Hull City's home defeat by Manchester United meant Newcastle only needed a point to survive but in a limp second half showing they failed to muster a shot on target.
Darron Gibson's superb strike sealed a winning end to Manchester United's season as Sir Alex Ferguson's second string proved too much for the battling Tigers.
Sunderland were beaten 3-2 by Chelsea at the Stadium of Light as Nicolas Anelka secured the golden boot. He lashed home a drive from 20 yards to give the Blues a 47th minute lead but Kieran Richardson equalised instantly.
A late Yossi Benayoun goal sealed Liverpool's win.
Arsenal thumped Stoke 4-1 at the Emirates. James Beattie's own goal began the rout while Robin van Persie netted twice for the Gunners. Abou Diaby added the other goal. The Potters could only muster a Ricardo Fuller penalty.
Two goals from Leon Osman helped Everton sink Fulham, who qualify for the Europa League, while Jason Roberts' red card was the only incident of note in the goalless draw between Blackburn and West Brom at Ewood Park.
Wigan beat Portsmouth 1-0 at the JJB thanks to Hugo Rodallega's goal.
At Eastlands, Felipe Caicedo's early strike was enough to beat Bolton Wanderers.