Three more sides seal places in Copa Libertadores
Argentina's Estudiantes, Brazil's Palmeiras and Universidad de Chile qualified for the Copa Libertadores group stage.
Three-time champions Estudiantes were without several key players against Perus Sporting Cristal and only advanced after a 76th minute header from 20-year-old Ramon Lentini saw the Argentinean side secure a 1-0 win and advance by virtue of the away goal scored in the 2-1 first leg defeat last week.
The wins sends Estudiantes into a group containing Brazil's Cruzeiro, Bolivia's Universitario and Deportivo Quito from Ecuador.
"We were better than them, but the Peruvians were dedicated to defending," said Estudiantes' former Manchester United midfielder Juan Sebastian Veron.
"It's very hard to play against a team like that. Thank God Lentini scored."
Universidad de Chile also advanced by virtue of the away goals rule against Mexico's Pachuca as a 1-0 first leg win sent them through after losing the second leg 2-1.
Universidad de Chile were up against it after just nine minutes as Mauricio Arias was sent-off and Pachuca took advantage as Gerardo Rodriguez converted a 24th minute penalty.
Marco Estrada equalised for Universidad de Chile in the second half before Damian Alvarez gave the Mexicans hope with four minutes remaining but they failed to find a crucial third.
Universidad de Chile will play in group seven alongside Brazil's Gremio, Bolivia's Aurora and Colombia's Boyaca Chico.
Finally in Bolivia, 1999 champions Palmeiras eased to a 2-0 win over Real Potosi as Cleiton Xavier and Keirrison scored to wrap up a comfortable 7-1 aggregate victory.
Palmeiras will now face defending champions Liga de Quito from Ecuador, Chile's Colo Colo and Brazil's Sport Recife in group one.