Blackburn Rover's goalkeeper Paul Robinson is a doubt for England's World Cup qualifying game against Kazakhstan on October 11 after picking up an injury in the Carling Cup.
It means he is unlikely to figure in the Wembley clash on October 11 - and also calls into question his availability for the match in Belarus four days later.
It is a big blow for England coach Fabio Capello, who recalled Robinson to the squad for last month's World Cup qualifying double header and has seen his regular number one David James concede ten goals in his past two games for Portsmouth.
Blackburn boss Ince has also expressed his disappointment at Robinson's enforced absence.
He said: "Paul was fantastic against Fulham (last Saturday) and made some world class saves.
"He is a man's man and wants to prove a point. So when he came off so early in the game (on Wednesday) you knew something wasn't right. He would not come off for no reason."
Welsh international keeper Jason Brown is expected to replace Robinson for matches against Newcastle and Manchester United.