MEXICO CITY, April 14 (Reuters) - Guadalajara survived a late fightback to beat America 3-2 in a meeting of Mexico's two biggest clubs, piling on the misery for their opponents. The defeat at the Jalisco stadium in Sunday night's game extended America's winless domestic run to 10 matches and left Mexico's richest team rooted to the bottom of Group Two with eight points from 14 games. Guadalajara, who claim to be the country's most popular club and field only Mexican players, stayed top of Group Three with 29 points. Midfielder Sergio Santana headed Guadalajara in front in the 39th minute and swept home Omar Bravo's pass for the second two minutes later. America's troubles were compounded with Juan Carlos Silva sent off on the hour for a second bookable offence. Sergio Avila added a third for Guadalajara shortly afterwards. But the visitors hit back when Paraguay striker Salvador Cabanas converted a penalty in the 77th minute and scored again three minutes later. Atlas, who beat Argentina's Boca Juniors in the Libertadores Cup last week, crashed 6-1 to Santos Laguna. Argentine Matiuas Vuoso scored a hat-trick and Ecuador forward Christian Benitez notched two. Santos stayed top of Group Two with 24 points. Defending champions Atlante were held 1-1 by Necaxa, their seventh draw in 14 games and stayed fifth in Group Two with 13 points.