LONDON -- Seven-time FA Cup champion Liverpool was knocked out of the competition on Saturday in a shocking 2-1 loss to lower-league club Barnsley.
Brian Howard scored the winner in the 90th minute of the fifth-round match at Anfield that put Barnsley in the quarterfinals. Dirk Kuyt had put the Reds ahead, before Stephen Foster equalized for Barnsley, which is mid-table in the second-tier League Championship.
The Reds brought on England midfielder Steven Gerrard, but couldn't score largely due to a standout performance from goalkeeper Luke Steele, who was making his debut for Barnsley after moving to the club last week on loan.
Barnsley has won the FA Cup once -- in 1912 -- and was runner-up two years before that.
Manchester United dominated Arsenal 4-0 at Old Trafford, with the Gunners finishing with 10 men after Emmanuel Eboue was sent off in the 49th.
Darren Fletcher scored twice, with Wayne Rooney and Luis Nani adding a goal each.
Defending champion Chelsea beat League One club Huddersfield 3-1, with Frank Lampard scoring in the 18th and 60th minutes and Salomon Kalou adding the other goal in the 70th.
Bristol Rovers reached the quarterfinals for the first time in 50 years by upsetting Southampton 1-0. Roman Bednar scored twice for West Bromwich Albion in a 5-0 win over Coventry, and Cardiff beat Wolves 2-0 in another all-League Championship matchup.
On Sunday, Sheffield United hosts Middlesbrough and Portsmouth travels to Preston.
MILAN, Italy -- Inter Milan increased its lead of the Serie A with David Suazo scoring twice in a 2-0 win over Livorno.
Suazo headed in a cross in the 14th minute and then scored again four minutes later after a defensive melee in the Livorno area.
The win gives Inter 59 points, 11 more than second-place AS Roma and 15 more than Juventus. Roma and Juventus played each other later Saturday.
Also Saturday, AC Milan plays at Parma. A win would put Milan into fourth place one point clear of Fiorentina, which plays Catania on Sunday.
BERLIN -- Werder Bremen gained a share of the Bundesliga lead with a 2-0 win over FC Nuremberg.
Ivan Klasnic continued his comeback from two kidney transplants by heading in Bremen's second goal in the 81st minute. Bremen led from the 30th, when Sweden forward Markus Rosenberg capitalized on a defensive blunder.
The victory pulled Bremen into at 40 points with league leader Bayern Munich, which faces a tough match Sunday at Hannover 96.
Also Saturday, Mario Gomez scored twice and Thomas Hitzlsperger scored the winner in injury time to lift Stuttgart to a 3-2 victory over MSV Duisburg.
Bayer Leverkusen goalkeeper Rene Adler made a string of stops to salvage a 2-2 draw against Karlsruher SC. Leverkusen scored through Simon Rolfes and Stefan Kiessling. Karlsruhe got goals from Sebastian Freis and Joshua Kennedy.
Also Saturday, it was: Borussia Dortmund 2, Energie Cottbus 0; Hansa Rostock 1, Eintracht Frankfurt 0; and Hertha Berlin 1, Arminia Bielefeld 0. On Friday, VfL Wolfsburg edged Schalke 2-1.
PARIS -- Le Mans upset six-time defending French league champion Lyon 1-0 off a goal from Tulio De Melo.
The Brazilian forward flicked in a cross from Ibrahim Camara that was diverted by Hassan Yebda at the near post in the 71st minute.
Lyon still tops the standings with 49 points, but second-place Bordeaux can cut the lead to one point if it beats Monaco on Sunday.
GLASGOW, Scotland -- Celtic warmed up for the visit of FC Barcelona in the Champions League with a 3-0 win over Hearts in the Scottish Premier League.
Andreas Hinkel scored his first goal for Celtic, with Jan Vennegoor of Hesselink and Scott McDonald adding goals.
Celtic, which hosts FC Barcelona on Wednesday in the Champions League round of 16, now trails league leader Rangers by one point. Rangers plays Sunday at Kilmarnock, when Hiberian hosts Aberdeen.
Rangers lead with 56 points, followed by Celtic with 55. Motherwell is third with 41 points after its 3-1 win over Gretna.
Patrick Cregg and Scott Arfield both scored twice for Falkirk in a 4-0 win over St. Mirren, and Inverness Caledonian Thistle and Dundee United drew 1-1.