West Ham manager Alan Curbishley admits he might have to make an emergency purchase before the transfer window closes on Friday following Kieron Dyer's broken leg at Bristol Rovers.
Curbishley has already seen Freddie Ljungberg, Scott Parker and Julien Faubert sidelined and lost Dyer in the first half against Rovers last night.
Dyer was stretchered from the pitch at the Memorial Stadium, and a series of X-rays last night have revealed the 28-year-old fractured the tibia and fibula in his right leg.
A statement on club website said: 'It is too early to say at this stage how long the player will be out for as this will become clearer once the first stage of surgery is completed.'
Curbishley said: 'At the moment I feel the luck is against us.
'I am sitting there with £20million worth of players out injured. It's disappointing but we have just got to get on with it and that's what the squad is for.
'We are treading on eggshells. It is a little bit delicate for us at the moment.
'I will have to assess it but that right-hand side - who would want to come and play for us with what has happened there?'
It seems unlikely that Brazilian striker Adriano will be at Upton Park by the weekend.
The club confirmed talks with Inter Milan about a loan deal but Curbishley was in the dark and Adriano is reported only to be interested in a permanent move.
He said: 'I don't know too much about it to be fair. I don't know if it is talk to stir things up, we will have to see. Is it speculation or is there anything in it? I don't really know.'
The Hammers boss described his side's 2-1 Carling Cup success at the Memorial Stadium as 'immaterial' once Dyer was hospitalised and insisted Rovers winger Joe Jacobson had been reckless with his challenge
He said: 'The Bristol Rovers player has got to be very disappointed with his tackle. As far as I can see he has lashed out after losing the ball and caught Kieron in a difficult area.
'Wouldn't you be angry? The players could see he lashed out. We are delighted to get through but after 10 or 15 minutes the game was immaterial after you get an injury like that.'
Craig Bellamy scored twice before the break with Rovers substitute Andy Williams pulling one back to set up a breathless finish.
Rovers manager Paul Trollope defended Jacobson.
He said: 'Joe is an honest lad and he swung his leg to get the ball. It was just an unfortunate incident.'
The result ended a 14-match unbeaten run for Rovers but Trollope added: 'We can take a lot of positives.
'A couple of poor bits of defending in the first half gave us a mountain to climb but we managed to put them under pressure, scored a good goal and maybe could have had an equaliser.'