ROME -- Defending champion Inter Milan was held to a 1-1 draw by Udinese, and European champion AC Milan rolled to a 3-0 win at Genoa as the title favorites opened the Italian league season Sunday.
Inter defender Ivan Cordoba headed the ball into his own net following an Udinese corner kick in second-half injury time. Dejan Stankovic had put Inter ahead 9 minutes in, but Inter was reduced to 10 men when goalkeeper Julio Cesar was sent off for a handball outside the area in the 56th.
Kaka scored twice and Massimo Ambrosini added another as Milan cruised against Genoa, which returned to Serie A after a 12-season absence.
Milan fans were barred from the match for fears of violence. Genoa fan Vincenzo Spagnolo was stabbed to death during a brawl with Milan supporters outside Luigi Ferraris stadium in 1995 and the two clubs had not met since.
Also, as temperatures soared above 104 degrees F, Napoli's return to the top division after six years was ruined with a 2-0 loss to visiting Cagliari.
Fiorentina beat Empoli 3-1 in a Tuscan derby with goals from Gianpaolo Pazzini, Adrian Mutu and Riccardo Montolivo.
Former Roma forward Vincenzo Montella scored an 86th-minute winner as Sampdoria beat Siena 2-1.
Catania's 19-year-old Japanese forward Takayuki Morimoto scored once and set up another goal in a 2-2 draw with Parma.
Reggina and Atalanta drew 1-1. Nicola Amoruso headed in for Reggina in the 77th and Cristiano Doni converted a penalty for Atalanta in the 84th.
AS Roma, fresh off its Italian supercup win last weekend, opened at Palermo later.
LONDON -- Manchester United won its first game of the Premier League season, with Nani scoring his debut goal in a 1-0 victory over Tottenham.
Nani's 68th-minute winner came after a frantic period of play during which Tottenham striker Dimitar Berbatov had two shots saved.
It was only the second goal scored this season by defending champion United. The Red Devils have drawn two and lost one of their previous games.
Also Sunday, Julio Arca scored a late goal to earn Middlesbrough a 2-2 tie against Newcastle.
Shortly before Nani's goal, Berbatov's attempt went through the legs of United goalkeeper Edwin van der Sar but defender Rio Ferdinand beat the Bulgarian to clear it off the line.
Soon after, Berbatov was in another position to score, but the ball was stopped by the chest of United defender Wes Brown.
United striker Carlos Tevez also had an attempt cleared off the line before Nani curled a long shot into the top of the net.
Tottenham has never won at Old Trafford in the Premier League. Its last win at United was a 1-0 victory in December 1989 in the former first division.
AMSTERDAM, Netherlands -- Ajax rallied to beat SC Heerenveen 4-1 in the Dutch first division with Luis Suarez scoring two goals.
After beating De Graafschaph 8-1 in the first round, Ajax has now scored 12 goals in two games. Kennedy Bakircioglu and Robbert Schilder also scored for Ajax.
Roy Makaay converted a penalty kick in the 21st minute as Feyenoord routed NAC Breda 5-0. Nuri Sahin scored twice before Ron Vlaar and Jonathan de Guzman each added goals. Breda has yet to win.
Also Sunday, it was: FC Twente 2, FC Utrecht 2; and FC Groningen 0, De Graafschap 2.
Ajax, Feyenoord, PSV Eindhoven and Vitesse Arnhem have six points from two matches.