LONDON -- Sevilla kept its UEFA Cup title defense on track while 2005 champion CSKA Moscow was eliminated and Ajax's poor European season finally ended on Thursday.
Sevilla had a 3-0 aggregate victory over Steaua Bucharest to reach the final 16. Striker Aleksandr Kerzhakov had the only goal of the second leg when he scored on a header past goalkeeper Cornel Cernea in first-half injury time off a cross from Andreas Hinkel.
Three other Spanish clubs also made the fourth round -- Osasuna, Celta Vigo and Espanyol.
CSKA Moscow lost 1-0 to Maccabi Haifa to exit by the same aggregate score, and while Ajax beat Werder Bremen 3-1, it couldn't overcome its 3-0 first-leg loss.
AZ Alkmaar, Bayer Leverkusen, Newcastle, Benfica, Shakhtar Donetsk, Rangers, Paris Saint-Germain, Lens and Braga also advanced. But no Italian teams qualified after Parma and Livorno lost.
Leonardo, Klaas-Jan Huntelaar and Ryan Babel scored for Ajax in Amsterdam, but it wasn't enough to stop the German club advancing.
The loss was the culmination of a poor European campaign for Ajax, which failed to qualify for the Champions League group stage. Ajax won the last of its four European Cup titles in 1995; it also won the 1992 UEFA Cup.
Maccabi Haifa beat CSKA 1-0 in Israel after a 0-0 draw in Moscow.
Israel international player Roberto Colautti scored the winner in the 14th minute from close range after CSKA goalkeeper Igor Akinfeev had stopped a shot from Alain Masudi.
Leverkusen, the 1988 champion, advanced 3-2 on aggregate to reach the final 16 for the first time in 12 years.
Celta Vigo, which is struggling in the relegation zone of the Spanish league, eliminated Spartak Moscow 3-2 on aggregate after a 2-1 win.