ROME, Jan 11 (Reuters) - AS Roma set up an Italian Cup quarter-final against Juventus when they beat third division Napoli 2-1 on Wednesday to complete a 5-1 aggregate win.
They were joined in the last eight by AC Milan, who won 4-3 at Brescia for a 7-4 aggregate win, while Udinese and Sampdoria edged through against Atalanta and Cagliari respectively.
Juventus crushed Fiorentina 4-1 in the second leg of their fourth round tie for a 6-3 aggregate victory on Tuesday.
The match in Rome was played behind closed doors in an empty Olympic Stadium following trouble between rival fans during Roma's 3-0 win in the first leg in Naples in December.
Even so, a second-string Roma side had little trouble mastering twice Italian champions Napoli.
Alberto Aquilani gave them the lead in the 39th minute, firing home from close range after a scuffed clearance.
Brazilian winger Mancini, who was making his first competitive appearance after a two-month injury layoff, grabbed their second just before the interval.
Nicolas Amodio got a consolation goal for Napoli in second-half stoppage time.
In Brescia, Milan played in fits and starts, going two up in the opening half hour through Clarence Seedorf and Filippo Inzaghi before Simone Del Nero struck back for Brescia just before halftime.
Rui Costa restored Milan's two-goal cushion in the 60th minute, curling the ball round the keeper at the end of a fine solo run.
A Luigi Di Biagio penalty, after visiting keeper Zeljko Kalac fouled Marius Stankevicius, and a Marck Hamsyk strike looked to have earned Brescia a draw on the night.
But Federico Agliardi brought down Inzaghi in the area two minutes from time allowing Rui Costa to dispatch Milan's winner from the penalty spot.
Sampdoria's game against Cagliari was the most dramatic.
With the teams level at 1-1 after the first leg, Francesco Flachi's 33rd minute goal seemed to have set Sampdoria on their way to the quarter-finals until the fourth minute of stoppage time when Massimo Gobbi headed an equaliser.
Less than a minute later, though, Flachi chested down a long ball in the area, held off his marker and fired home to give Sampdoria a 3-2 win on aggregate with the last kick of the tie.
Their next opponents will be Udinese, who were given a fright by Atalanta before winning 3-1 to seal a 3-2 win on aggregate.
Stefano Mauri gave the home side an early lead but Luca Ariatti's 69th-minute equaliser for Atalanta left Udinese needing at least two more goals to avoid going out.
Mirko Pieri pulled one back with a superb volleyed drive after 78 minutes and Antonio Di Natale completed Udinese's great escape from the penalty spot eight minutes from time after Ariatti's clumsy challenge on Valerio Bertotto.