Managerless Tottenham Hotspur will meet former boss Juande Ramos in the Round of 32 of the Europa League after being drawn against Ukraine outfit Dnipro Dnipropetrovsk.
Ramos managed Spurs for one year from October 2007 before being sacked with the club in the relegation zone following their worst-ever start to a Premier League campaign. And now he will get the chance to return to White Hart Lane when the two sides meet in February, with the first leg in Eastern Europe.
Spurs sacked Andre Villas-Boas on Monday morning, meaning they are looking for a new man to spearhead their European campaign and a bid to return to the Champions League.
The winners of the tie will be at home first against PAOK or Benfica in the following round.
Swansea have been handed a tough test, having been paired with unlucky Champions League drop-outs Napoli -- who failed to secure a top-two finish despite earning 12 group points -- with the second leg in Naples. The winners will face another tough meeting in the Round of 16 with either FC Porto, another Champions League team, or Eintracht Frankfurt though they will be at home in the second leg.
Juventus, who have added interest in reaching the final with it being played in their Turin home, must again travel to Turkey, this time to take on Tranzonspor. Juve were knocked out of the Champions League last week with a 1-0 loss to Galatasaray in Istanbul. They could then face an all-Italian tie with a date against Esbjerg or Fiorentina lined up.
Ligue 1 side Lyon will play Chornomorets Odesa, also from Ukraine, before facing the winners of the all-Champions League tie between Viktoria Plzen and Shakhtar Donetsk.
The Round of 16 could also throw up the Seville derby, that is if Sevilla oust NK Maribor and Real Betis get past Rubin Kazan.