Ghana coach Kwesi Appiah has promised his team will "not disappoint the nation'' when they take on Sudan in African World Cup qualifying Group D on Friday.
Ghana head into their fourth pool game one point behind leaders Zambia and looking to steal a march on the 2012 African champions, who host Lesotho on Saturday.
"Football unites everyone in Ghana and that urges us on. We will do our possible best to win all the games ahead of us to reach the World Cup finals,'' Appiah, who has a fully-fit squad at his disposal, said on his FA's website before departing for Omdurman.
"We have to go far and will not disappoint the nation.''
In Friday's other game, Libya and Congo DR go head to head in Tripoli, both knowing victory would take them top of Group I - at least until current leaders Cameroon visit Lome on Sunday to tackle bottom-placed Togo.
Only the 10 group winners will advance from this round of qualifying, with five two-legged ties in October and November then set to determine which teams will represent Africa at the 2014 World Cup finals in Brazil.
Tunisia can guarantee their progress from Group B by beating Sierra Leone in Freetown on Saturday - if Equatorial Guinea fail to overcome Cape Verde Islands in Praia.
"We must dictate the pace of the game to gain a psychological edge over the opposition,'' Tunisia coach Nabil Maaloul said at a press conference. "We need to pressure them in their area and deny them space.''
Elsewhere on Saturday, Group E leaders Ethiopia will be looking to continue their unbeaten start to the pool campaign when they play bottom-placed Botswana in Lobatse. South Africa will be keen to capitalise on any slip-up by defeating Central African Republic in Yaounde.
Group J leaders Senegal travel to Luanda to take on Angola on Saturday, while Uganda face Liberia in Kampala.
Group C pace-setters Ivory Coast visit Bakau for their game against Gambia, with second-spotted Tanzania tackling Morocco in Marrakech.
Congo will be aiming to maintain their 100% record in Group E by picking up three points against Gabon in Franceville. The other two teams in the pool, Niger and Burkina Faso, do battle in Niamey on Sunday.
Egypt can advance from Group G by toppling Zimbabwe on Sunday - if Guinea do not defeat Mozambique in Conakry. Egypt coach Bob Bradley has urged his players to display the right attitude, particularly if things go against them in Harare.
"Before I got here I heard the mentality of playing outside Egypt was not very good,'' the American said at a press conference. "From the very beginning I told the players that in order to qualify for the World Cup that has to change, has to improve.
"What the players need to understand is that when we play outside Egypt the conditions, sometimes the field or referees, won't go your way. But the strength of the group and the mentality (to) not let those things stop us is the key.''
Also on Sunday, Algeria head to Porto Novo to play Benin level on six points atop Group H alongside Mali, who meet bottom-placed Rwanda in Bamako.
Information from the Press Association was used in this report