FC Utrecht took a stranglehold on the play-off for Europa League qualification as they secured a 2-0 first-leg victory at FC Twente.
Cedric van der Gun opened the scoring inside the first ten minutes and Twente goalkeeper Sander Boschker's air-shot presented Edouard Duplan with an open goal shortly before the hour mark.
Go Ahead Eagles took a giant step towards the Eredivisie with a 3-0 win over Volendam in the first leg of their promotion play-off.
The Deventer club have already denied Volendam promotion once this season, beating them 3-1 on the final day of the regular season and allowing Cambuur Leeuwarden to snatch the Eerste Divisie title.
They were in the mood to inflict further punishment as Xander Houtkoop put them ahead in the eighth minute on Thursday evening. They had to wait until the last 20 minutes to add to their lead, Jarchinio Antonia doing the honours, and after Volendam had Paul de Lange sent off, Marnix Kolder made it three to all but seal Go Ahead's promotion ahead of Sunday's return leg.
Sparta Rotterdam earned a 0-0 draw at home to Roda JC, denying the top-flight side an important away goal.
Donovan Deekman could even have snatched an advantage for the second-tier side in injury time but was denied by a good save from Filip Kurto.
Information from the Press Association was used in this report