Juventus moved to the brink of retaining the Serie A title on Sunday afternoon with a late 2-0 victory at Torino.
The visitors made the breakthrough four minutes from time through Arturo Vidal, prompting a frantic final few minutes at Turin's Stadio Olimpico.
Torino defender Kamil Glik was sent off for a second bookable offence in the 90th minute, with Claudio Marchisio then grabbing a stoppage-time goal to seal the away win.
With just 12 points left to play for, the result moved Antonio Conte's side 11 points clear at the summit.
Palermo moved out of the Serie A relegation zone and dealt Inter Milan's hopes of European football next season a blow with a hard-fought 1-0 win.
Josip Ilicic scored the only goal of the game after only 10 minutes to lift the hosts out of the bottom three on goal difference.
Defeat left Inter in seventh, two points off a Europa League place.
AC Milan regained third place with a 4-2 win over Catania at the Stadio Giuseppe Meazza, sealed by a Mario Balotelli penalty.
Catania took a surprise lead in the 30th minute when Nicola Legrottaglie prodded home Francesco Lodi's free-kick, despite Milan's dominance in front of goal.
But Milan headed into the break with greater momentum as Mathieu Flamini swept home Kevin-Prince Boateng's pass from close range.
In an end-to-end encounter, Catania restored their lead after 65 minutes thanks to a delicate chip from Gonzalo Bergessio who latched onto the end of a Pablo Barrientos through ball.
The visitors were unable to hold onto their lead as Milan equalised once again through Giampaolo Pazzini and the striker gave his side a lead for the first time in the match with his second goal just minutes later.
Milan looked comfortable at 3-2, but Balotelli ensured the Rossoneri remained in the final Champions League spot with a stoppage time penalty.
Siena's relegation worries increased this afternoon as Pablo Osvaldo's hat-trick helped European hopefuls Roma to an emphatic 4-0 victory at the Stadio Olimpico.
Osvaldo netted twice in the first half, with Erik Lamela on target in between, and then completed his treble midway through the second period.
The result lifted Aurelio Andreazzoli's side to fifth in the standings, while Giuseppe Iachini's side slumped to 19th following wins for fellow strugglers Palermo and Genoa.
Genoa picked up three crucial points in their battle against relegation with a narrow 1-0 win at Chievo.
Davide Ballardini's men came to life in the second half with Marco Borriello scoring the only goal of the game in the 74th minute to take the Rossoblu out of the bottom three thanks to Roma's win over Siena.
With four games of the season to go, Genoa are level on points with Palermo just above the bottom three, while Chievo are not mathematically safe yet with just a seven-point advantage over the relegation zone.
Adem Ljajic starred as Fiorentina cruised to a 3-0 victory away to Sampdoria, who played the last 10 minutes of the game a man short following the sending off of Daniele Gastaldello.
Ljajic ran the show for the visitors and against a team coached by former Fiorentina boss Delio Rossi, who lost that job following a violent altercation with the Serbian last May.
He scored the second just before the break, adding to Juan Cuadrado's opener, before setting up Alberto Aquilani for the third.
The victory boosted Fiorentina's hopes of qualifying for the Champions League.
Elsewhere, Lazio are three points off the last Europa League spot for next season after a goalless draw with Parma at the Stadio Ennio Tardini.
Information from the Press Association was used in this report.