Malaga boosted their hopes of a top-four finish in the Primera Division with a narrow 2-1 victory over mid-table Getafe at La Rosaleda.
Goals either side of half time by Roque Santa Cruz and Weligton put the hosts in control, before Juan Valera grabbed a consolation for Getafe with 15 minutes left.
Real Sociedad took a huge step towards Champions League qualification by beating their closest rivals for the position, Valencia, 4-2 in an enthralling game at Anoeta.
Roberto Soldado gave the visitors the lead midway through the first half but Inigo Martinez's volleyed goal put Philippe Montanier's side back on level terms.
Goals from Chory Castro and Imanol Agirretxe late in the second half appeared to have sealed the win for the Basques. However, Jonas pulled one back for Valencia just as injury time approached to set up a tense finish, before Agirretxe scored again to put the result beyond doubt.
Sevilla look consigned to a mid-table finish after playing out a 1-1 draw at Valladolid. Unai Emery's men went into the game knowing a win could have left them with an outside, but fighting chance of making Europe next season.
But they left Jose Zorrilla with a point that leaves them off the pace - Alvaro Negredo's second-half penalty giving them a share of the spoils after Javi Guerra's opener.
It was not what they wanted but they ended up paying the price for simply not being able to get the better of an inspired Jaime Jiminez. The well-travelled goalkeeper was equal to everything thrown at him in open play and it took a free hit from the 12-yard spot to beat him.
Granada pulled themselves clear of the relegation zone after holding out for a narrow 1-0 victory away to Espanyol.
A superb free-kick by Nolito was enough to see off Javier Aguirre's side, who were the better team throughout the match but were unable to take their chances.
Information from the Press Association was used in this report