Wolves climbed out of the Championship relegation zone thanks to three first-half goals which proved enough to see off battling local rivals Birmingham 3-2 in a full-bloodied derby at St Andrew's.
A devastating 17-minute spell stunned the home crowd into silence and proved enough to secure Wanderers' fourth win in five games, as well as their first league double over their neighbours in 14 years, despite a valiant fightback from the hosts.
Cardiff moved seven points clear at the top of the Championship with a comfortable 3-0 victory over Blackburn.
Fraizer Campbell nodded home his sixth for the club from five yards out to finally break the Rovers resistance five minutes before the break. And it was Campbell's replacement Joe Mason who doubled the lead with four minutes to go before substitute Peter Whittingham wrapped up the points from the penalty spot in added time.
Leicester's play-off hopes were dealt another major blow as they suffered a third straight league defeat at Barnsley, going down 2-0.
Nigel Pearson's side have slipped from second to seventh having failed to win in March and just once in their last 10 outings. However, Barnsley, who started the afternoon in the bottom three after Saturday's defeat to fellow strugglers Sheffield Wednesday, did not look like a side fighting the threat of relegation as they made it a hat-trick of wins at Oakwell and could even afford a missed penalty.
Ten-man Blackpool made sure Ian Holloway's return to Bloomfield Road ended in defeat as they beat Crystal Palace 1-0 to secure a result that has implications at both ends of the Championship table.
With Hull and Watford not playing until Tuesday night, Palace could have moved to within three points of the second-placed Tigers but they were undone by Matt Phillips' 85th-minute strike, despite playing against 10 men for 48 minutes.
Lewis McGugan's stoppage-time penalty provided an uncharacteristically exciting finally to a dreary Championship encounter at Turf Moor as Nottingham Forest extended their unbeaten run with a 1-1 draw against Burnley at Turf Moor.
Sam Baldock crashed home his first goal of the year in stoppage-time to snatch a point for bottom club Bristol City and deal Sheffield Wednesday's Championship survival hopes a blow in a 1-1 draw.
Millwall and Ipswich laboured to a goalless draw at a blustery Den to earn a point apiece and keep themselves out of harm's way in the npower Championship.
Ipswich stretched their unbeaten run to four matches and hit the 50-point mark while FA Cup semi-finalists Millwall remain a point better off.
In the late game, Jake Buxton's 87th-minute header earned Derby a 2-1 win against a Leeds side who are starting to look anxiously over their shoulders towards the drop zone.
Buxton's bundled effort came just seconds after the Rams were denied a penalty when Michael Jacobs was brought down in the box.
Prior to that Paul Coutts had netted the rebound from a missed Conor Sammon spot kick, which came just six minutes after substitute Ross McCormack's 67th-minute opener for United.
As a result of the win Derby remain comfortable in mid-table and, although Leeds are one of the other sides in and around them, they are starting to slide.
Information from the Press Association was used in this report.