Fluminense moved a step closer to landing Brazil's Apertura with a 1-1 draw at Sao Paulo.
The Rio de Janeiro side have a nine-point lead with just four matches to play after Fred's goal midway through the second half earned them a point, following Luis Fabiano's 50th-minute goal for the home side.
Second-placed Atletico Mineiro missed the chance to make ground on the leaders, as Deivid's ninth minute penalty saw them lose 1-0 at Coritiba.
Second half goals from Juan Manuel Martinez and substitute Guilherme Torres gave Corinthians a 2-0 win at Atletico Goianiense, with the result confirming Atletico's relegation.
Elicarlos scored twice in the first half to set up Nautico Recife's 3-0 win over Internacional, with Kieza wrapping up the win in the 62nd minute.
Felipe Azevedo, Hugo and Henrique got themselves on the score sheet as Sport Recife won 3-0 at Vasco da Gama, while Rodrigo Souza's 78th minute goal gave Bahia a 1-0 win at Portuguesa.
Botafogo twice led at Palmeiras through Nicolas Lodeiro and Elkeson but Hernan Barcos scored twice to earn the home side a 2-2 draw.
Information from the Press Association was used in this report