French Coup de la Ligue holders Marseille's attempts to defend their crown were ended as Paris St Germain beat them 2-0 to dump them out of the competition.
A Thiago Silva penalty and Jeremey Menez goal sealed the win for PSG and continued their domestic dominance. Coach Carlo Ancelotti opted to rest his star man Zlatan Ibrahimovic for the tie.
Marseille's Rod Fanni was shown a red card in the 28th minute for a foul on Guillaume Hoarau in the box, which led to Silva opening the scoring from the spot.
Nice are also through to the last eight after a 3-1 win over Lyon, characterised by an electric opening quarter-of-an-hour during which all four goals were scored.
Valentin Eysseric put Nice ahead with a sixth-minute penalty only for Bafetimbi Gomis to level for the visitors inside 60 seconds.
Mahame Traore wasted little time in restoring the lead, netting in the ninth minute and Renato Civelli made it three in the 15th.
Remarkably there was no more scoring in the next 75 minutes, but Milan Bisevac was red carded for Lyon two mintues from time.
Montpellier edged the final match of the evening 1-0, Jonathan Tinhan's goal on the hour seeing off Bordeaux.
Saint-Etienne v Paris-SG
Montpellier v Nice
Rennes v Troyes
Bastia/Auxerre v Lille