QPR will be without Anton Ferdinand, Fabio Da Silva and Armand Traore at Tottenham this weekend, with playmaker Adel Taraabt also a doubt.
Manager Mark Hughes said he would "have to move people around" to deal with the defensive crisis as he looks to build on the encouraging point won at home to Chelsea last weekend.
"We've got a number of injuries at the back," Hughes said. "Anton Ferdinand is not going to be involved. Fabio isn't available - he'll be out for a number of weeks. To compound that, Armand Traore is not available either. We're going to have to move people around to accommodate for that.
"Adel Taraabt didn't complete the training session today, so we'll have to check him tomorrow. He felt a little bit of tightness so he may not be available tomorrow."
Meanwhile, new signing Stephane Mbia may have to wait for his debut after Hughes revealed that he was unlikely to feature at White Hart Lane.