Napoli capped a superb week with a well-deserved 1-0 win over Inter Milan to heap further pressure on Nerazzurri coach Claudio Ranieri.
Marchese scores a wonder goal (UK/US/ROI only)
Inter had already slipped to seventh place in Serie A and trail Marseille 1-0 in their Champions League last-16 tie, while Napoli are enjoying a strong domestic run and beat Chelsea in midweek.
Napoli stayed true to the form book with a deserved win on home soil on Sunday as Ezequiel Lavezzi's strike on the hour made the difference, despite the late dismissal of Salvatore Aronica.
German Denis struck a hat-trick as Atalanta cruised past nine-man Roma with a thumping 4-1 win in Bergamo.
Guido Marilungo put the hosts ahead early on and Denis made it 2-0 after 19 minutes. Fabio Borini reduced the deficit before half-time, but Denis struck his second shortly after the restart.
Roma's hopes of a comeback suffered a blow when the team's leading scorer Daniel Osvaldo was sent off with 36 minutes to go.
Denis completed his hat-trick in the 66th minute and Roma's misery was complete when they were reduced to nine men, substitute Marco Cassetti seeing red for dissent eight minutes from time.
The result moved the Bergamaschi to 11th place as Roma's top-four hopes suffered a blow.
Udinese kept up their Serie A title push with a 3-1 victory at Bologna.
Antonio Di Natale put the visitors in front from the penalty spot in the 38th minute and Dusan Basta doubled their advantage early in the second half.
Panagiotis Kone gave the hosts hope by halving the deficit in the 81st minute only for Antonio Floro Flores to put the match to bed and keep Udinese in third place.
Lazio ended a difficult week on a high with a 1-0 win over Fiorentina at the Stadio Olimpico.
Miroslav Klose scored the only goal of the game in the 36th minute as Lazio got back to winning ways after defeats to Atletico Madrid and Palermo over the last seven days.
Siena took full advantage of playing for almost 90 minutes with an extra man by beating Palermo 4-1 at the Stadio Artemio Franchi.
Federico Balzaretti was sent off after only a minute of the game and, although Igor Budan gave the Rosaneri the lead in the 12th minute, Siena soon turned things around to comfortably win a one-sided game.
Claudio Terzi brought them level from the penalty spot in the 23rd minute before goals from Erjon Bogdani, Luca Rossettini and Franco Brienza sealed all three points for the Tuscans, who maintain their two-point cushion over the relegation zone.
Lecce picked up three vital points in their quest for safety with a 3-1 win at Cagliari.
Luis Muriel put the Apulians ahead just before the break, but Joaquin Larrivey levelled for the home side from the penalty spot in the 50th minute.
Thiago Ribeiro hit the post for the home side before Andrea Bertolacci gave Lecce all three points in the 61st minute. To make matters worse for Cagliari, they ended the game with 10 men after Michele Canini saw red late on.
Davide Moscardelli made it a miserable start to life as Cesena coach for Mario Beretta as his goal earned Chievo a 1-0 win at the Stadio Dino Manuzzi.
In a tense game characterised more for the number of yellow cards - seven - and a red card for Cesena's Maurizio Lauro, Moscardelli struck late on to earn the Flying Donkeys all three points.
Catania extended their unbeaten run at home to five games with a 3-1 triumph over relegation-threatened Novara.
Gonzalo Bergessio put the hosts ahead on the half-hour mark before Giovanni Marchese doubled Catania's lead early in the second half. Alejandro Gomez made it 3-0 in the 55th minute before substitute Raffaele Rubino scored a consolation goal for Novara six minutes from time.