In-form Melbourne Heart had their five-match winning streak broken on Wednesday as Adelaide United scored a 3-1 victory at AAMI Park.
Without Brazilian captain Fred, the Heart struggled to create chances, while for Adelaide goals either side of the half-time break to Sergio Van Dijk (penalty) and Dario Vidosic gave the visitors a comfortable cushion.
New Reds coach John Kosmina was ensured the win when Van Dijk sealed his brace in the 79th minute. While striker Eli Babalj made up for a glaring miss earlier in the match by scoring a late consolation for second-placed Heart.
A brilliant brace from departing striker Matt Simon has helped Central Coast Mariners defeat Melbourne Victory 2-0 in an energetic A-League fixture at Bluetongue Stadium.
The win sees the Mariners take their unbeaten streak to 11 matches and gives them a six-point buffer at the top of the table.
Simon, playing his last game for the club before moving to Korean side Chunnam Dragons, opened the scoring after just 20 seconds when he converted Troy Hearfield's cross.
Bernie Ibini-Isei hit the post for the hosts in the second-half before Simon capped a memorable farewell with his second of the game in the 84th minute.
Brisbane Roar climbed to second on goal difference after they were held to a 3-3 draw at Perth Glory.
The hosts established a two-goal advantage when Billy Mehmet set up Travis Dodd with 16 minutes gone at nib Stadium before Mile Sterjovski lashed home a 20-yard drive eight minutes later.
However, Brisbane replied with two goals shortly before half-time. First, Mitch Nichols reduced the arrears in the 40th minute with a shot from the edge of the box and Erik Paartalu then nodded in Luke Brattan's corner.
They then went in front midway through the second period when Nichols latched onto Paartalu's ball over the top and he chipped keeper Danny Vukovic.
Perth, though, earned a share of the spoils with 10 minutes to go when Ivan Franjic fouled Sterjovski in the box and the latter held his nerve to fire home the penalty.
Gold Coast United remain bottom of the table after a spirited fightback was thwarted in a 3-2 defeat to Newcastle Jets at Ausgrid Stadium.
Jeremy Brockie broke the deadlock with a header from Nikolai Topor-Stanley's cross two minutes before the interval and grabbed his and Newcastle's second in the 64th minute when he brought down Ryan Griffiths' pass and found the back of the net.
Gold Coast battled back through Ben Halloran's first-time strike and Adama Traore's goal but substitute Labinot Haliti fired home the winner 11 minutes from time.
Wellington Phoenix inflicted Sydney FC's second away loss of the season when they triumphed 4-2 at Westpac Stadium.
Sydney took the lead after 15 minutes when Vince Lia was penalised for handling in the box and Brett Emerton converted, but the hosts drew level nine minutes later when Jamie Coyne committed the same offence and Daniel Cortes made no mistake from the spot.
Wellington then went in front four minutes before the break when Dani Sanchez chipped Sydney keeper Liam Reddy but Bruno Cazarine levelled in the 63rd minute after being sent clear by Emerton.
Phoenix regained their advantage with 13 minutes remaining when Ben Sigmund headed home Leo Bertos' corner and Paul Ifill wrapped up the points in stoppage time with the substitute firing into the bottom corner.