Cesc Fabregas looks set to pull out of the Spain squad to face Ecuador on Wednesday after picking up an ankle injury during Barcelona's tour of Malaysia.
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Fabregas, 26, was forced to leave the pitch following a heavy challenge ten minutes before the end of Barca’s 3-1 win against a Malaysia XI on Saturday.
A statement on the club’s official website read: “Cesc Fabregas had a number of tests this morning after arriving back from Malaysia to measure the extent of the ankle injury he picked up in Saturday's match.
“It has subsequently been confirmed that the player has sprained a ligament in his right ankle.
“Club doctors have contacted the Spanish FA to recommend that the player should not join the national squad for the friendly against Ecuador so that he can undergo treatment in Barcelona.''
Fabregas, who this week pledged his future to Barca after a summer of being pursued by Manchester United, is one of five players from the Catalan club to have been called up by Spain coach Vicente Del Bosque for the Ecuador friendly.
Information from the Press Association was used in this report