La Liga president Javier Tebas has said he believes the time is right for the Spanish game to take off in the U.S.
Champions Atletico Madrid, Real Madrid and Barcelona are poised to lead attempts to crack the American market, with Tebas saying competitive matches could one day be played there.
The Telegraph quoted the president as saying he believed La Liga was the "best league in the world" and could stake its claim to a key place in the American sporting market.
"We have fans in every corner of the globe, and we want to deliver our product in any format necessary," he said.
"Today we play in Spain, but the future has no frontiers. We are the best league in the world. La Liga will continue to work on our global format so that our league can be visible the world over. From here, anything is conceivable."
Real and Atletico have already played in the U.S. this summer, and Tebas said he was confident the level of interest in them showed Spanish football would be a huge draw for American fans.
Nearly 110,000 people attended Real's 3-1 Champions Cup defeat to Manchester United in Michigan on Saturday -- the biggest-ever crowd for a soccer match in the States.
"The US is the sports marketplace par excellence," Tebas said. "It is the place where any global spectacle must prove its worth, where success is sought in terms of market, strategy and product.
"We want to be able to create and deliver Spanish football there. The best league in the world, the competition in which the best players in the world compete, wants to be able to pass the test of the most demanding sports fans on the planet."
He said "now is the moment" for the sport to take off in the U.S. and stressed: "La Liga considers the U.S. a priority. We will work with all our available resources to reach the American public with a level of excellence which our product represents.
"Our challenge is to reach the millions of potential fans in the U.S. If this comes to pass, La Liga as a brand will be in the best showcase in the world."