Goalkeeper Chris Smith is the only absentee for Stenhousemuir due to a knee injury as they welcome in-form Hearts to Ochilview just three days after losing 5-4 to Stirling Albion.
Manager Scott Booth said: "This will be a very difficult game but it is a great one to have to help get over the Stirling display. We are normally a side that does not lose a lot of goals but we had a crazy spell on Saturday.
"What we have to do is concentrate on the good things and look to do more of them. We also need to cut out the mistakes as Hearts will be even more ruthless than Stirling."
Hearts are set to make "six or seven changes" for the clash but will have a more experienced team than the one that lost 4-0 to Livingston in the Petrofac Training Cup last week.
Osman Sow and Jamie Walker are suspended while goalkeepers Neil Alexander (broken cheekbone) and Scott Gallacher (ankle) are injured along with Callum Paterson (knee) and Dale Carrick (thigh).
Assistant head coach Stevie Crawford told HeartsTV: "We were disappointed with the outcome of last week's game against Livingston, result-wise, but we're a development club and we're going to give youngsters opportunities.
"We want to win football games and progress to the next round of the cup. We'll hopefully have learned our lesson from last week.
"We've got to get a happy medium. I said last week that we want to win football games and Livingston was a good gauge of where boys are at. At 2-0 we did go under a bit too easy for our liking but young players are going to learn from that.
"Tuesday night, when we're talking about changes, it will be boys with more first-team experience who have been chapping on the door. With it being the League Cup, it's important that we progress to the later stages."