Takayuki Seto netted a 90th minute equaliser for Astra Giurgiu, who came from behind twice to level the game against Genk.
Sardar Azmoun finishes off good team build-up and a cleverly dummied-ball to put a bow on Rostov's win over Sparta Prague.
Eric Dier says while Spurs showed more aggression, they didn't create nearly as many chances.
Alexandre Lacazette scored twice for Lyon as they cruised past AZ Alkmaar 4-1 in their Europa League round of 32 first leg.
Gustavo Blanco marked his full debut with a goal as Shakhtar Donetsk edged Celta Vigo, 1-0, in the Europa League.
FC Copenhagen won 1-2 at Ludogorets in the Europa League to put themselves in a commanding position for the second leg.