Claude Puel is used to being an underdog but his intense work ethic and Southampton's sneaky skill are capable of springing a shock at Wembley.
Neither Jose Mourinho or Man United are strangers to silverware and on Sunday the two hope to combine for their first of many together in the EFL Cup.
Martin Caceres could be set for a dream Southampton debut in the EFL Cup final against Manchester United.
What role will Wayne Rooney have? Will Southampton benefit from a long rest? Which manager will emerge on top? Nick Miller previews the EFL Cup final.
Jose Mourinho has confirmed that Wayne Rooney and Michael Carrick will be in Manchester United's EFL Cup final squad but Henrikh Mkhitaryan is not fit
The match will be Southampton's first at Wembley since the 1979 League Cup final against Liverpool.