Iran's 1-0 win over China put them one step closer to World Cup qualification while Marcello Lippi's team are on the brink of elimination.
Japan, South Korea and Iran all secured key victories on Tuesday, in their quest to qualify for the 2018 World Cup finals in Russia.
Mehdi Taremi's shot trickled over the line as Iran earned a much needed 1-0 win over China in Group A.
Shinji Okazaki scored his first goal in 2017 as he gave Japan a 2-0 lead in their AFC World Cup Qualifier.
Syria will rue their plethora of missed chances as South Korea sealed a narrow 1-0 win.
Shinji Kagawa opened the scoring for Japan in their Asian 2018 World Cup Group B Qualifier versus Thailand.