The 28-year-old has 17 goals for Chelsea, but missed out on his country's last World Cup qualifiers due to injury.
FA chairman Greg Clarke has sent his thoughts to those affected by the Westminster terror attack and pledged to recognise all those involved.
Ruby Ledley is due to give birth to the couple's third child a few days after Wales take on the group leaders.
The Spanish football federation said he did not practice Wednesday as a "precaution" ahead of the team's World Cup qualifier against Israel on Friday.
Republic of Ireland assistant manager Roy Keane has said the way to handle Wales star Gareth Bale is to "hit him ... fairly."
The Wales manager returns to Dublin, where his father's ashes were spread after passing, to face the Republic of Ireland in a World Cup qualifier.