|10||West Bromwich Albion||5||0||8|
|16||Brighton & Hove Albion||5||-3||4|
|17||West Ham United||5||-6||4|
Marco Silva knows Watford's unbeaten run to start the season will be put to the test with a tough Man City clash.
Heaton, 31, who has been capped three times by England, suffered the injury after landing awkwardly during victory over Crystal Palace.
Sanches had a difficult Premier League debut in last weekend's home defeat to Newcastle following his shock switch from the German champions.
Manuel Pellegrini says Pep Guardiola got a wake-up call in his first year of coaching Man City but he "has no doubt" his successor will do well.
Tottenham will look to mount a meaningful challenge on four fronts with Davinson Sanchez and Serge Aurier's arrivals improving their depth.
Manchester United have agreed to sign 15-year-old midfielder Charlie McCann from Coventry.