Rashford, 19, is expected to be selected for Aidy Boothroyd's squad despite making just one appearance for the U21s, which came last September.
Ibrahimovic and Rojo suffered knee problems as United won 2-1 against Anderlecht at Old Trafford to progress to the semifinals of the Europa League.
As well as Premier League action, there's two huge FA Cup semifinals this weekend as Arsenal, Manchester City, Tottenham and Chelsea eye the final.
Former Arsenal defender Kolo Toure believes Arsene Wenger is the best manager Arsenal have had.
Manchester United manager Jose Mourinho believes Jones and Smalling need to take risks to help them qualify for Europe.