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The Liga leaders face Getafe, Eibar and Girona and their manager indicated he may rotate his squad.
Sid Lowe: It's true that Real Madrid have dropped an uncharacteristic number of points already this season, but there's no cause for concern. Yet.
Isco says he did not listen to any offers from other clubs, despite speculation that he considered moves to Barcelona, Manchester City and Juventus.
Gareth Bale has called for "calm" after an opening to the 2017-18 season that has not gone completely to plan for either him or Real Madrid.
Barcelona president Josep Maria Bartomeu has again said that Lionel Messi's father has signed a contract renewal on behalf of the Argentina forward.