|8||West Bromwich Albion||21||0||29|
|12||West Ham United||21||-9||25|
Costa, 28, trained alone at Cobham for three days and did not travel to Leicester City with the rest of the squad.
Spurs moved up to second in the table as Harry Kane's hat trick helped them see off the Baggies 4-0, but lost defender Vertonghen after 64 minutes.
Jose Mourinho's side head into the match on a nine-match winning run in which Mkhitaryan has been key.
Tottenham are in ominous form; their sixth straight Premier League win a 4-0 stroll over West Brom that kept up their title challenge momentum.
Harry Kane was exceptional, fully deserving 10/10 for his hat trick in Tottenham's 4-0 win over West Brom. Christian Eriksen was similarly impressive.
Everton boss Ronald Koeman feels his old friend Pep Guardiola may well have underestimated the physical intensity of the Premier League.