Vitesse bounced back from their midweek cup exit with an impressive victory over Ajax in Amsterdam.
Steven Bergwijn completed Utrecht's misery with a stunning individual effort as PSV ran riot at the Stadion Galgenwaard.
Real Madrid youngster Martin Odegaard, currently on loan at Heerenveen, has suggested that he has extended his contract with the European champions.
Manchester United midfielder Matty Willock has joined Dutch club FC Utrecht on loan.
Newcastle midfielder Siem de Jong has completed a permanent move back to Ajax as manager Rafael Benitez continues to clear the decks.