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Despite not qualifying for the 2018 World Cup, there are positives for the Black Stars to take from the failure.
KweséESPN identify the five matches which ultimately decided Africa's World Cup qualifiers.
Who were the continent's star performers during the weekend's qualifiers?
Stuart Baxter insists it is important for South Africa to finish their qualifying campaign with a flourish against Senegal on Tuesday.
While several of Africa's top names will be present at the World Cup, many have been left behind.
Edwin Gyasi's first Ghana goal cancelled out Shikabala's opener as the Black Stars end their World Cup qualifying campaign with a draw against Egypt.