With Manchester United struggling in recent seasons, have Liverpool lost their chance to to better their North-West rivals?
While Arsenal fans fret over Alexis Sanchez and Mesut Ozil's futures, Arsene Wenger must also start planning to sort his ageing defence.
The next four weeks are likely to be highly instructive for Tottenham, with several heavyweight showdowns and other important challenges.
Brighton host a struggling Everton while Southampton entertain Newcastle on Sunday.
Man United and Man City feature on Saturday, but will Palace finally end its winless drought versus Chelsea?
Former Manchester United midfielder Nicky Butt discusses what it means to Manchester United to get a win over their rivals, Liverpool.