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In a match Barcelona must win to maintain realistic title hopes, the club that exerts tactical control will have a clear advantage.
El Clasico is arguably the biggest game in club football each year, but just how does Barcelona vs. Real Madrid rate alongside other big matches?
Paco Alcacer is adamant that he's able to blank out the criticism after his Barcelona goal drought extended to 10 games in the draw against Hercules.
"We weren't able to [spend that much for Deco], so [Jorge Mendes] told us he had another really good kid. It was Ronaldo," Laporta said.
Earlier this week Marco Tronchetti Provera, the head of Inter's biggest sponsor, Pirelli, spoke of his dream of seeing Messi wearing an Inter shirt.
Real Madrid president Florentino Perez says Cristiano Ronaldo gives back more to the club than what they pay him.