Dybala notched his fifth league goal of the season five minutes into the contest at the Juventus Stadium.
Juventus got back to winning ways thanks to first half goals from Paulo Dybala and Gonzalo Higuain.
AC Milan coach Vincenzo Montella said his side "played on par with Napoli" despite suffering a 2-1 defeat at home on Saturday.
AC Milan paid the price for a poor start against Napoli. Vincenzo Montella's men played well, but in the end could not fight back from two goals down.
AC Milan are still in negotiations with Everton over a loan for Gerard Deulofeu, the Italian club's CEO Adriano Galliani says.
Luciano Spalletti firmly believes that Radja Nainggolan is worth as much as Pogba, calling him a 'complete footballer.'