Werder Bremen were the only top-flight casualties in the first round of the DFB-Pokal on Sunday as they were ousted by 3rd-division Sportfreund Lotte.
Gotze, who did not play in Dortmund's Supercup defeat to his old club Bayern Munich last weekend, took part in a friendly on Monday.
Leipzig became the first Bundesliga side to fall by the wayside in the DFB Pokal as the rest of the first-round ties went to form on Saturday.
Mats Hummels has said Bayern Munich are approaching optimum condition after their 5-0 win over Carl Zeiss Jena in the first round of the DFB Pokal.
Robert Lewandowski netted a hat trick to lift Bayern over Jena 5-0 in the first round of the DFB Cup.
Robert Lewandowski netted a hat trick and added an assist to lift Bayern over Jena 5-0 in the first round of the DFB Cup.