Denis Alibec's goal just before halftime gave Astra Giurgiu the advantage over Viktoria Plzen en route to a 2-1 win.
Nicolai Jorgensen's lone goal of the game saw Feyenoord top Zorya Luhansk 1-0.
Onyinye Ndidi assured Racing Genk of three points against Athletic Bilbao with a sensational strike from outside the box.
FK Qabala's Ricardinho mistimes his header gifting St Etienne a late 1-0 win.
Tarik Elyounoussi's beautiful strike was the standout of Olympiakos' flurry of goals as they cruised past Astana 4-1.
Paul Pogba scored twice as Manchester United eased to a comfortable 4-0 Europa League victory against Fenerbahce at Old Trafford.