Chile have never beaten Argentina away and Lionel Messi and company badly need a win to get their WC qualification off the ground.
Brazil will look to continue their winning run while Uruguay will try to protect their home record in Thursday's 2018 World Cup qualifier.
Chile will try to end Argentina's recent recovery in 2018 World Cup qualifying when the teams meet Thursday night in Buenos Aires.
Roberto Firmino insists he's ready to replace the injured Gabriel Jesus as Brazil's No. 9 for their upcoming World Cup qualifiers.