Nice finally managed to bag a 1-0 win courtesy of a goal by Alassane Plea against FC Salzburg.
Steaua Bucharest have yet to lose at home to Swiss opposition as they drew 1-1 with Zurich.
Wayne Rooney returns to the Manchester United starting XI for Thursday's Europa League clash against Fenerbahce.
Kovalenko opened the scoring from distance for Shakhtar, ending Gent's six game unbeaten run in European matches.
Schalke are now unbeaten in seven European away matches dating back to November 2014 as they downed Krasnodar.
Francesco Totti will make his 100th appearance in European competition after Roma coach Luciano Spalletti said he will play against Austria Vienna.