Napoli laid out their title credentials in style with a 3-0 win over 10-man Inter Milan at the San Siro taking them to the top of Serie A, ending Claudio Ranieri's winning start to life as manager of the Nerazzurri.
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A red card for Joel Obi and a dubious penalty decision in the 43rd minute helped Walter Mazzarri's side on their way to all three points as Claudio Ranieri saw his side lose for the first time since he took charge.
Marek Hamsik missed the spot-kick but Hugo Campagnaro scored the rebound and further goals from Christian Maggio and Hamsik in the second half earned Napoli all three points.
The result took them two points clear at the top and left Inter just one point above the bottom three.
Roma won their second game in a row to bring an end to Atalanta's unbeaten start to the season with a 3-1 triumph at the Stadio Olimpico.
Bojan Krkic opened his account for the Giallorossi in the 20th minute before Pablo Osvaldo added a second after half an hour.
German Denis opened the game up with a goal in the 48th minute, but Fabio Simplicio settled Roma's nerves with the winner nine minutes from the end.
The Giallorossi looked much more confident after last weekend's win over Parma.