Villarreal's spirited effort was not enough to overcome a 4 goal aggregate deficit, as Roma advance to the round of 16.
A dramatic late header from Kiese Thelin sends Anderlecht to the round of 16 on away goals.
Jason Dasey and PJ Roberts look ahead to MSL Week 6, as JDT aim to move up from the bottom half of the table.
MLSsoccer.com's Matt Doyle looks at the trend towards younger Designated Players and what that means for the league.
Karim Ansarifard's opener was the first of Olympiakos' three that helped the side down Osmanlispor and reach the last 16.
The Boys from Exploding Heads are here to assure you that the League Cup final is definitely not pointless.