Juventus could be without both Alex Sandro and Juan Cuadrado for their Champions League round-of-16 first leg game at home to Bayern Munich next week.
Defender Sandro picked up a thigh injury in training on Tuesday, with tests on Wednesday set to determine how long he will need to rest.
Winger Cuadrado is also set for further tests on the ankle injury he suffered during Juve's win over Napoli last weekend.
Turin newspaper La Stampa reported that both will miss Friday's game at Bologna and could sit out the Bayern match in an injury-ravaged season for Juventus.
In the absence of Sandro, Patrice Evra is likely to keep his place in the starting XI and may have to deal with former Juve forward Kingsley Coman in the Champions League.
The Frenchman moved to Bayern in the summer -- initially on a season-long loan but with an option for a permanent switch -- and Juve forward Alvaro Morata told Sport Bild: "Coman is one of the players with the most potential I have ever seen.
"When he was at Juve, he was forced to play in the centre of the midfield and he didn't have much in the way of tactical freedom.
"He had to play with his back to goal, which is not really what he does best -- and that is to run at his opponents at pace, like he is doing now."
Arturo Vidal is also set to line up for Bayern against the side he left in the summer, while Morata could also face Xabi Alonso, his teammate and mentor during their time at Real Madrid.
"He was one of the few people who really cared for me [in Madrid]," Morata said. "He would always keep an eye on the younger players in the first team."