Germany coach Joachim Loew could be without Per Mertesacker, Mesut Ozil and Miroslav Klose for the forthcoming friendlies against Italy and England.
A virus had ruled Arsenal centre-back Mertesacker out of Arsenal’s 1-0 defeat to Manchester United on Sunday, and while teammate Mesut Ozil did appear at Old Trafford he has also contracted the illness.
On Monday, the German Football Association (DFB) announced that neither player will be present when the Germany squad meets in Munich ahead of the two games. However, the DFB did not reveal whether they were expected to be available before the flight to Milan on Thursday.
Lazio striker Klose has travelled to Munich but is unlikely to be available for either Friday's game in Italy or Tuesday's game in England.
The 35-year-old, who has just returned from a foot injury, damaged his shoulder in Lazio’s 1-1 draw against Parma and will be examined by DFB doctors in Munich on Monday.
With 68 goals, Klose is currently tied at the top of the Germany all-time scorer list with legendary striker Gerd Mueller.